YK-11 Powder | 1 Gram
YK-11 is a Selective Androgen Receptor Modulator (SARM) that functions as a gene-specific agonist of the androgen receptor (AR) in MDA-MB 453 cells. The way YK-11 operates is unique, affecting various anabolic pathways. It has been found to display more significant anabolic activity in vitro in C2C12 myoblasts than dihydrotestosterone (DHT).
YK 11 Mechanism of Action
The way YK-11 promotes muscle growth and key myogenic regulatory factors in skeletal muscle tissue is of particular interest. Factors such as myogenic differentiation factor (MyoD) and myogenic factor 5 (Myf5) are activated to a much greater extent than by DHT. This helps explain why YK-11 exerts its selective modulation of the AR.
Unlike testosterone and most other agents mediated by androgen receptors that promote anabolic growth, YK-11 can be taken orally, meaning injections are not necessary for proper absorption. It’s important to note that YK-11 is currently intended for laboratory research use only, and its side effects are not yet fully understood.
Follistatin Effects on Muscles
What differentiates YK-11 from other SARMs is a key aspect of its anabolic activity that is modulated via the expression of follistatin. This was uncovered by measuring the difference in effects when co-administering anti-follistatin antibodies with YK11.
Follistatin has been demonstrated to boost insulin-stimulated glucose and amino acid uptake into skeletal muscle cells, which in turn enhances insulin sensitivity and increases skeletal muscle mass. Follistatin proteins also serve the crucial function of blocking inhibitory ligands from binding to Transforming Growth Factor-ß.
Perhaps one of the most exciting aspects of follistatin’s action is its binding and neutralization of catabolic proteins like Activin A, Activin B, and Myostatin. A significant challenge is that follistatin proteins themselves are quickly broken down through proteolysis and have limited bioavailability and half-life, even with direct injection into wasting muscles.
YK-11, however, stimulates the body to produce more follistatin proteins both systemically and locally. This may circumvent the direct follistatin administration’s limitations and contribute to muscle growth.
YK11 Applications
In summary, YK-11 stands out in the world of SARMs, demonstrating unique anabolic effects. Its ability to selectively modulate the AR and enhance follistatin expression holds promising potential.
Yet, comprehensive understanding and application of YK-11 remain in the realm of research, and further studies are needed to fully grasp its potential benefits and risks, especially concerning human use.
Data on our YK-11 Powder for sale
CAS Number: 1370003-76-1
Formula: C25H34O6
Molar Mass: 430.541 g/mol
Class: Myostatin Inhibitor, Selective Androgen Receptor Modulator
Storage: Store in a cool dry place away from direct sunlight to maximize shelf life.
- Foil Pouch with UV resistance to minimize degradation.
- Minimum 98% pure.
- 1,050 Milligrams YK-11 per pouch.
- Measuring tools not included.
Disclaimer
The information provided above is not intended to substitute medical advice, diagnosis, or treatment. Should you have any questions regarding a medical condition, seek the advice of your physician or a qualified healthcare provider. In no case should medical advice be disregarded or delayed because of what you have read or seen. We bear no responsibility or liability for your use of any of our research compounds and products. Please note that they are being sold for research purposes ONLY. We do NOT condone any personal use.
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