BPC 157 – 5mg
Body Protection Compound-157 (BPC-157) is a synthetic peptide derivative of a protein found in human gastric juice in the GI tract called Body Protection Compound (BPC). Although it is a smaller peptide, 15 amino acids in total, BPC 157 has been found to have many of the same properties as its parent molecule, such as wound healing, blood vessel growth, gut health, and nitric oxide generation.
BPC157 also modulates immune system function, gene expression, and hormone regulation in gastrointestinal nervous system as well as the coagulation cascade. Most data on BPC 157 peptide is derived from animal models and limited data is available from clinical trials.
BPC 157 and Cellular Protection
BPC-157 helps to regenerate damage by causing fibroblast cells to multiply and migrate more easily and improving synthesis of proteins such as collagen, fibrin, and elastin. Similar effects of BPC 157 peptide may be seen on endothelial cells, which are responsible for lining blood vessels.
Studies conducted on rats and chicken embryos found that BPC 157 significantly boosts production of new blood vessels and the growth of collateral blood vessels, suggesting that BPC-157 could one day be used for stroke and heart attack subjects. Further investigation is needed on the cytoprotective effects of BPC 157.
BPC 157 and Peripheral Tissue Healing
BPC-157 studies have shown positive findings in animal studies on tendon, ligament, bone, and skin burns. With connective tissue injuries, limited blood flow can hinder how quickly fibroblasts and other wound repairing cells are carried to the injury site limiting tendon healing.
According to research done on rats, BPC-157 has been shown to improve the growth factor in collateralization and density of fibroblasts around tendons, ligaments, muscle tissue, and bones after injuries take place, and promote vascular growth. Collateral blood vessel growth is also an area of keen interest with respect to research on BPC 157 since vascular growth may significantly augment the wound healing process in tissues that are otherwise limited by poor blood supply, like ligament injuries.
BPC 157 has also shown effectiveness in counteracting corticosteroid-impaired muscle healing.
BPC 157 peptide and Antioxidant function
Animal studies have shown that BPC-157 functions as an antioxidant and can protect against oxidative stress. In a research study, when BPC 157 peptides were used on rats, they had lower levels of nitric oxide and malondialdehyde, two indicators for tissue damage due to free radicals. BPC 157 may have similar effects within mammal gastric juices but clinical trials are needed.
This is further supported by additional research which has shown that BPC-157 can decrease production of reactive oxygen species in the gastrointestinal tract. Studies have shown that a modified form of lactococcus lactis bacteria increased levels of BPC 157 in cell culture, indicating that BPC 157 may play a role in probiotic modulation of gastrointestinal wound healing.
BPC157 and Gastrointestinal Health
Since BPC157 is a derivative of a natural compound in human gastric juices, it is of particular interest in clinical research on gut health and for treating inflammatory bowel disease, leaky gut, and stomach ulcers. BPC 157 peptide plays a role in the brain gut axis and naturally strengthens and protects the mucosal barrier of the digestive tract. This form of tissue repair is what it is currently best known for. In a rat model of esophagitis untreated for 12-20 months, when given directly into the stomach, BPC 157 peptide therapy instantaneously recovered disturbed lower esophageal and pyloric sphincter pressure suggesting an accelerated healing process resulting from BPC 157.
It also antagonized other alcohol effects, including acute and chronic intoxication. In another study conducted on rats with short-bowel syndrome over 4 weeks, BPC 157 therapy yielded a significant increase in weight beyond preoperative values when administered orally or parentally.
Furthermore, villus height, crypt depth and muscle thickness increased significantly with this in rats treated with BPC157. Rats with ischemia and colitis in another study experienced significant improvements in blood flow and local nitric oxide utilization after administration of BPC 157, with virtually no remaining lesions and only minimal adhesions after only 10 days of treatment. More research is needed on the effects of BPC 157 on Crohn’s disease, gastric ulcers, and other gastrointestinal pathologies.
Data on our BPC-157 for sale
CAS Number: 137525-51-0
Formula: C62H98N16O22
Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Molar Mass: 1,419.5 g/mol
Half life: 4 hours
Class: Polypeptide
Storage: Keep refrigerated upon reconstitution.
- Lyophilized sample in sterile glass vial.
- Minimum 98% pure.
- 5mg BPC-157 per vial.
- Diluent and laboratory supplies not included.
Disclaimer
The information provided above is not intended to substitute medical advice, diagnosis, or treatment. Should you have any questions regarding a medical condition, seek the advice of your physician or a qualified healthcare provider. In no case should medical advice be disregarded or delayed because of what you have read or seen. We bear no responsibility or liability for your use of any of our research compounds and products. Please note that they are being sold for research purposes ONLY. We do NOT condone any personal use.
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